Daniel Coleman built one of the most beloved children's YouTube channels: Danny Go, something that had children laughing and moving and enjoying the screen, but today, Coleman is stepping away from all of that to share what probably is the hardest news of his life. His 14-year old son Isaac passed away on May 21, after a long fight with cancer.The Danny Go star announced Isaac's passing on Instagram on May 22, sharing a black-and-white photograph of the two of them together. In the caption he said there was so much he wanted to say but didn't yet know how. He talked about scrolling through thousands of old photos and videos in the days before Isaac died, and feeling, alongside the grief, something that surprised him: tremendous pride.Coleman wrote,Your 14 years were full of so many challenges, but you met them all with such grit…and you somehow kept your trademark joy in spite of it all. You truly had a spark like no other, Isaac! Remembering how loved you were and how full of life your time here was gives me great comfort. Being your dad was the honor of a lifetime. I’m so proud of you and I love you forever. Rest peacefully, son.More details about Danny Go creator's son and his diagnosis View this post on Instagram Instagram PostIsaac had been born with Fanconi anemia, a rare genetic condition that disrupts bone marrow function and significantly raises a person's lifetime risk of developing cancerous tumors. Coleman had known for years that this was a possibility, that cancer was something Isaac's condition almost inevitably pointed toward. In December 2025, when Isaac was first diagnosed, Coleman wrote on Instagram that while the family had always braced for this, it was still a shocking thing to actually hear about your child. The cancer was discovered through a biopsy and classified as stage 3 mouth cancer. Surgery was scheduled for early January 2026, with the initial goal of removing the tumour entirely. When surgeons went in, though, they found the cancer had spread further than pre-surgical scans had shown. They ended up removing significantly more teeth and mouth tissue than anticipated, and had to take a skin graft from Isaac's leg to rebuild the soft tissue in his mouth, which was a brutal procedure for a teenager to recover from.Doctors told the family that the cancer's classification sat right at the border between stage 3 and stage 4, but because of Isaac's underlying Fanconi anemia diagnosis, the treatment options available to him were far more limited than they would have been for a typical pediatric cancer patient. Isaac Coleman lived 14 years that, by any measure, were harder than most. He went through transplants, surgeries, and a cancer diagnosis that would have broken most adults, and apparently did all of it while keeping a sense of joy that his own father couldn't stop writing about. Danny Go built a show designed to bring light into kids' lives and right now, the people who love that show are trying to bring a little of that light back to him.Danny Go is available to stream on YouTube