Grey's Anatomy is an American medical drama TV show that focuses on the professional and personal lives of surgical interns, attendings, and residents at the Seattle Grace Mercy West Hospital and Grey Sloan Memorial Hospital. Recently, on January 29, Patrick Dempsey appeared on The Tonight Show with Jimmy Fallon for the promotion of his new series and to celebrate his 60th birthday.Dempsey discussed his new thriller, Memory of a Killer, danced with Reggie Miller, and recalled the moment when David Bowie interrupted Enchanted filming. At the end of the episode, he reflected on Grey's Anatomy as well as his lasting McDreamy legacy.This article will explore what actually happened in that episode and what Patrick Dempsey said about his journey while performing the role of Dr. Derek Shepherd in Grey's Anatomy.Continue reading more about the story.Patrick Dempsey looks back on his journey on Grey's Anatomy View this post on Instagram Instagram PostDuring The Tonight Show on January 29, 2026, Patrick Dempsey shared his journey as Dr. Derek Shepherd with Jimmy Fallon. Jimmy started the conversation with a picture of Derek.Jimmy:"The whole world loves you from Grey's Anatomy. I think it gets bigger and bigger and bigger and bigger."Patrick:"Oh, whoa. Thank you. It's incredible. I think they're on their 29th season or something crazy like that. But I did 11 seasons, I think 237 episodes, something like that. But it's incredible. The best thing that's come out of this show, though, is I meet so many young people that have gone into the medical profession which is needed right now more than ever. Certainly our nurses and everything like that. And that's the thing I'm proud of. And we had an incredible cast of characters and everything."Jimmy:"Do you remember any of the jargon that you'd have to learn?"Patrick:"None whatsoever. I can't remember a thing. Because it's like cramming for a test, right? You get this terminology and you're like, what am I talking about here? I have no idea. But I know MRI.I can do that one. You know, CAT scan. And the most important, stat. So that's it."Jimmy:"Okay, that's great. Okay, this is all good. Wow. Wow"Dempsey became nostalgic during the show, The Tonight Show, and shared his statistics that he contributed to Grey's Anatomy. He said that he was a part of the show for eleven seasons and filmed more than two hundred episodes. According to him, the most rewarding part was meeting new people who went to medical field after watching this medical drama.Dempsey felt that the people who became nurses and doctors were inspired by watching the show. He also recalled moments in the production set when he made friends with other cast members. The fun thing about this Instagram reel is that Patrick laughed and admitted that he forgot most of the things about medical jargon. He compared it to cramming for a test and said that he only remembers simple words like CAT scan and MRI.Follow Soap Central for more updates on Grey's Anatomy.