Scrubs Season 10 cast and characters: Every returning star and new appearances in the upcoming revival series

Scrubs Season 10 ( Image via YouTube / ABC )
Scrubs Season 10 ( Image via YouTube / ABC )

Scrubs returns formally with its tenth season on ABC, which will air on February 25, 2026. More than 16 years after the original series concluded, this revival brings viewers back to Sacred Heart Hospital, combining the familiar humor of the original cast with the energy of newly introduced characters.

The two initial episodes will be aired back-to-back, and the series will be available to stream on Hulu the following day.

Besides the nostalgia factor, the revival series also explores how the characters have evolved over the past 10 years, both professionally and personally.


Core returning cast of Scrubs Season 10

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The show will bring back its three main characters from season: Zach Braff will return as Dr. John Michael "J.D." Dorian, while Donald Faison will play Dr. Christopher Turk, and Sarah Chalke will portray Dr. Elliot Reid.

Scrubs' main character, J.D., brings three styles of performance to the role through his comedic timing and emotional depth. Faison brings his character to life through chemistry, physical comedy, and friendship, which made Turk a delightful character from the start. The series provides both dramatic and comedic relief through Elliot. Chalke shows her character's dual professional and personal development.

The Scrubs dynamics remain constant in their show, and the newly developed season allows for creative experimentation.


Confirmed guest and recurring appearances in Scrubs Season 10

Recurring or guest roles are played by several original characters in addition to the main cast. John C. McGinley once again takes on the role of Dr. Perry Cox, who appears in about three episodes to give his mentorship and quick wit. Judy Reyes reappears as Nurse Carla Espinosa in four episodes, showcasing her life as a working mother. Christa Miller will be back as Jordan Sullivan, and Robert Maschio will play Todd “The Todd” Quinlan, bringing humor to some of the storylines.

Neil Flynn (The Janitor) is officially confirmed to return, and this way, the series is guaranteed to have one of the most unpredictable and memorable characters.

The new guest stars, who are confirmed, are Rachel Bilson as Charlie, Andy Ridings as Wes, and Lisa Gilroy as Lily.


When was the Scrubs Reboot announced?

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In July 2025, ABC officially announced the revival of Scrubs, with the main cast and some recurring actors on board.

The presence of Braff, Faison, and Chalke in the capacity of executive producers guarantees continuity of voice, character, and format of the story, though there is a chance of the introduction of modern storytelling methods.


What viewers can expect

The audience can look forward to the same dynamics of Scrubs. The friendship between J.D. and Turk remains central to the plot, which gives it both heart and humor. The character arcs of Elliot remain significant, providing both professional and personal ones.

The chemistry of the ensemble, which the audience remembers, is sustained by the use of recurring characters such as Dr. Cox, Carla, Todd, Jordan, and The Janitor, and new dimensions are provided by the new characters - Charlie, We,s and Lily- which contribute to the Sacred Heart story.

Much of the humor and personality-driven story from the original Scrubs is also present in the re-imagining. It allows the show to explore contemporary social and work-related topics. One may anticipate that a blend of old jokes, emotional undertones, and fresh plots will be introduced in the hospital setting.

The Scrubs revival is a sign of networks returning to old series to connect with their hardcore fans and appeal to the new ones. The approach by ABC serves as evidence of considering a well-balanced mix of established casting methods, new cycles, and hybrid distribution.

The show retains the humor, ensemble dynamics, and storyline of the original, but adapts to the current viewing demands, such as those of streaming platforms. The revival is also an act of how nostalgia can coexist with new content, resulting in a product loved across generations.


Scrubs Season 10 will air on February 25, 2026, on ABC.

Also Read: Brand new preview of Scrubs reveals new details about the reboot

Edited by Nimisha